Select A LocationTulissin® 25
(tulathromycin injection)
Injectable Solution
Product Description
Tulissin® 25 Injectable Solution is a ready-to-use sterile parenteral preparation containing tulathromycin, a semi-synthetic macrolide antibiotic of the subclass triamilide. Each mL of Tulissin® 25 injectable solution contains 25 mg of tulathromycin.
Key Features
Take a New Breath™
If you trust your herd with tulathromycin, then you need Tulissin® 25 injectable solution.
Tulathromycin, a first choice therapy1 for treating Swine Respiratory Disease (SRD):
- Goes to work in minutes2
- Concentrates in the most susceptible areas of the respiratory system
- Provides nine days of lung activity to treat and control SRD3
- Convenient dosages with availability of Tulissin® 100 (tulathromycin injection) for use in large pigs with the same pre-slaughter withdraw time of five days
Tulissin® 25 (tulathromycin injection) Tulissin® 100 (tulathromycin injection)
IMPORTANT SAFETY INFORMATION FOR SWINE
Ensure a pre-slaughter withdrawal time of five (5) days in swine. Do not use in animals known to be hypersensitive to the product.
- Villarino N, Brown SA, Martin-Jimenez T. Understanding the pharmacokinetics of tulathromycin: a pulmonary perspective. J Vet Pharmacol Ther. 2014;37(3):211-221.
- Waag TA, Bradford JR, Lucas MJ, et al. Duration of effectiveness of tulathromycin injectable solution in an Actinobacillus pleuropneumoniae respiratory-disease challenge model in swine. J Swine Health Prod. 2008;16(3):126–130.
- Benchaoui HA, Nowakowski M, Sherington J, Rowan TG, Sunderland SJ. Pharmacokinetics and lung tissue concentrations of tulathromycin in swine. J Vet Pharmacol Ther 2004;27(4):203-210.
Label Indications and Dosage
Swine
Tulissin® 25 Injectable Solution is indicated for the treatment of swine respiratory disease (SRD) associated with Actinobacillus pleuropneumoniae, Pasteurella multocida, Bordetella bronchiseptica, Haemophilus parasuis, and Mycoplasma hyopneumoniae; and for the control of SRD associated with Actinobacillus pleuropneumoniae, Pasteurella multocida, and Mycoplasma hyopneumoniae in groups of pigs where SRD has been diagnosed.
DOSAGE AND ADMINISTRATION
Swine
Inject intramuscularly as a single dose in the neck at a dosage of 2.5 mg/kg (1 mL/22 lb) Body Weight (BW). Do not inject more than 4 mL per injection site.
Table 1. Tulissin® 25 Swine Dosing Guide (25 mg/mL)
| Animal Weight(Pounds) | Dose Volume(mL) |
| 4 | 0.2 |
| 10 | 0.5 |
| 15 | 0.7 |
| 20 | 0.9 |
| 22 | 1.0 |
| 25 | 1.1 |
| 30 | 1.4 |
| 50 | 2.3 |
| 70 | 3.2 |
| 90 | 4.0 |
Suckling Calves, Dairy Calves, and Veal Calves
BRD – Tulissin® 25 Injectable Solution is indicated for the treatment of bovine respiratory disease (BRD) associated with Mannheimia haemolytica, Pasteurella multocida, Histophilus somni, and Mycoplasma bovis.
DOSAGE AND ADMINISTRATION
Calves
Inject subcutaneously as a single dose in the neck at a dosage of 2.5 mg/kg (1 mL/22 lb) body weight (BW). Do not inject more than 11.5 mL per injection site.
Table 2. Tulissin® 25 Calf Dosing Guide (25 mg/mL)
| Animal Weight(Pounds) | Dose Volume(mL) |
| 50 | 2.3 |
| 75 | 3.4 |
| 100 | 4.5 |
| 150 | 7.0 |
| 200 | 9.0 |
| 250 | 11.5 |
Withdrawal Period
RESIDUE WARNINGS
Swine
Swine intended for human consumption must not be slaughtered within 5 days from the last treatment.
Calves
Calves intended for human consumption must not be slaughtered within 22 days from the last treatment with Tulissin® 25 Injectable Solution. This drug is not for use in ruminating cattle.
Packaging
- 100 mL bottle, 250 mL bottle
Formulation
- 25 mg of tulathromycin/mL
FDA Status
Approved by FDA under ANADA # 200-668.
Swine
Swine
Tulissin® 25 Injectable Solution is indicated for the treatment of swine respiratory disease (SRD) associated with Actinobacillus pleuropneumoniae, Pasteurella multocida, Bordetella bronchiseptica, Haemophilus parasuis, and Mycoplasma hyopneumoniae; and for the control of SRD associated with Actinobacillus pleuropneumoniae, Pasteurella multocida, and Mycoplasma hyopneumoniae in groups of pigs where SRD has been diagnosed.
DOSAGE AND ADMINISTRATION
Swine
Inject intramuscularly as a single dose in the neck at a dosage of 2.5 mg/kg (1 mL/22 lb) Body Weight (BW). Do not inject more than 4 mL per injection site.
Table 1. Tulissin® 25 Swine Dosing Guide (25 mg/mL)
| Animal Weight(Pounds) | Dose Volume(mL) |
| 4 | 0.2 |
| 10 | 0.5 |
| 15 | 0.7 |
| 20 | 0.9 |
| 22 | 1.0 |
| 25 | 1.1 |
| 30 | 1.4 |
| 50 | 2.3 |
| 70 | 3.2 |
| 90 | 4.0 |
Suckling Calves, Dairy Calves, And Veal Calves
Suckling Calves, Dairy Calves, and Veal Calves
BRD – Tulissin® 25 Injectable Solution is indicated for the treatment of bovine respiratory disease (BRD) associated with Mannheimia haemolytica, Pasteurella multocida, Histophilus somni, and Mycoplasma bovis.
DOSAGE AND ADMINISTRATION
Calves
Inject subcutaneously as a single dose in the neck at a dosage of 2.5 mg/kg (1 mL/22 lb) body weight (BW). Do not inject more than 11.5 mL per injection site.
Table 2. Tulissin® 25 Calf Dosing Guide (25 mg/mL)
| Animal Weight(Pounds) | Dose Volume(mL) |
| 50 | 2.3 |
| 75 | 3.4 |
| 100 | 4.5 |
| 150 | 7.0 |
| 200 | 9.0 |
| 250 | 11.5 |
The labeling contains complete use information, including any cautions and warnings. Always read, understand and follow the labeling and use directions. See the reverse side for use directions and additional information.