Pharmgate Animal Health establishes a presence in Canada and announces the first North American approval for Aivlosin®.

December 15, 2011— Pharmgate Animal Health, the joint venture between ECO Animal Health Ltd of London, England and Pharmgate LLC of Ramsey, New Jersey is pleased to announce the formation of Pharmgate Animal Health Canada Inc. to distribute its parents’ veterinary products in the Canadian livestock and poultry markets. The new company has named Marc Loomes, Colin Gray and Bill Maxwell as Directors.

The company has also announced the Canadian approval of ECO’s new macrolide antibiotic, tylvalosin (Aivlosin Water Soluble Granules®) for the treatment of porcine proliferative enteritis (PPE) associated with Lawsonia intracellularis infection in swine. The granules are administered in drinking water for five consecutive days at a low inclusion rate of 50ppm to provide 5mg tylvalosin per kg body weight daily thus offering both a low dose rate and short treatment duration.

Tylvalosin is rapidly absorbed, widely distributed to target tissues, extensively metabolized and rapidly excreted. It thus lends itself to situations where rapid treatments in the face of acute outbreaks are required. The meat withdrawal period is 24 hours—another benefit when breakdowns occur in late finishers. The in-water delivery system also offers the farmer the flexibility to treat individual pens or barns—features that are not often possible with in-feed medications.

In a North American multi-centre study1 using the Winkelman challenge model, clinical scores and lesions scores were significantly reduced in treated pigs. There were no deaths due to PPE in the treated pigs compared with 14.9% deaths in the un-medicated controls and the production parameters of ADG and Feed Conversion were also significantly improved by Aivlosin treatment.

Edward Seed, VP of Sales & Marketing for Pharmgate Animal Health, N. America, summarizes “Aivlosin Water Soluble Granules offer the swine producer a rapid, cost effective and flexible solution for the treatment of subclinical, chronic and acute cases of ileitis in pigs with a 24 hour withdrawal period. Importantly, with global concerns about the use of antibiotics this new treatment with its therapeutic dose rate and short treatment time fulfills the requirement for judicious use”.

Aivlosin® is a registered trademark of ECO Animal Health Ltd.
1ECO Animal Health study report EFF.US.050080 on file.