{"id":6094,"date":"2022-07-14T10:28:06","date_gmt":"2022-07-14T15:28:06","guid":{"rendered":"http:\/\/pharmgate.com\/usa\/?page_id=6094"},"modified":"2026-02-19T14:17:32","modified_gmt":"2026-02-19T20:17:32","slug":"tenotryl","status":"publish","type":"page","link":"https:\/\/pharmgate.com\/usa\/tenotryl\/","title":{"rendered":"Tenotryl"},"content":{"rendered":"\n<h1>\n\t\tTenotryl<sup>\u00ae<\/sup>\n\t<\/h1>\n\t<h3>(enrofloxacin)<br \/>\nInjectable Solution<\/h3>\n\t\t\t\t<img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/pharmgate.com\/usa\/wp-content\/uploads\/sites\/5\/2018\/01\/Aivlosin-species-577x75.png\" alt=\"Aivlosin-species-577x75\" itemprop=\"image\" height=\"75\" width=\"577\" title=\"Aivlosin-species-577x75\" onerror=\"this.style.display='none'\"  \/>\n\t\t\t<a href=\"\/usa\/wp-content\/uploads\/sites\/5\/2022\/08\/VIR_Tenotryl-Swine_Full-Page-Label_FINAL_0622.pdf\" target=\"_blank\" rel=\"noopener\">\n\t\t\t\t\t\tPrescribing Information\n\t\t\t\t\t<\/a>\n\t\t\t<a href=\"https:\/\/pharmgate.com\/usa\/wp-content\/uploads\/sites\/5\/2025\/10\/Virbac-Tenotryl-Product-Profile-Sheet_10.9.25.pdf\" target=\"_blank\" rel=\"noopener\">\n\t\t\t\t\t\tProduct Profile Sheet\n\t\t\t\t\t<\/a>\n\t\t\t<a href=\"\/usa\/wp-content\/uploads\/sites\/5\/2022\/07\/Tenotryl_SDS_GHS_04112022.pdf\" target=\"_blank\" rel=\"noopener\">\n\t\t\t\t\t\tSafety Data Sheet\n\t\t\t\t\t<\/a>\n\t\t\t<a href=\"https:\/\/pharmgate.com\/wp-content\/uploads\/2022\/07\/VIR_Tenotryl_Product-Info-Sheet_V2_FINAL_0622_REF.pdf\" target=\"_blank\" rel=\"noopener\">\n\t\t\t\t\t\tTenotryl Info\n\t\t\t\t\t<\/a>\n\t\t\t\t\t\t<h4>Product Description<\/h4>\n\t\t\t<p>Tenotryl\u2122 (enrofloxacin) injectable solution is indicated for the treatment and control of swine respiratory disease (SRD) associated with\u00a0<em>Actinobacillus pleuropneumoniae, Pasteurella multocida, Haemophilus parasuis, Streptococcus suis, Bordetella bronchiseptica\u00a0<\/em>and<em>\u00a0Mycoplasma hyopneumoniae.<\/em><\/p>\n<p>Tenotryl\u2122 (enrofloxacin) injectable solution is also indicated for the control of colibacillosis in groups or pens of weaned pigs where colibacillosis associated with\u00a0<em>Escherichia coli<\/em>\u00a0has been diagnosed.<\/p>\n\t\t\t\t\t\t<h4>Key Features<\/h4>\n<p><strong>Swine:<\/strong><\/p>\n<strong>Target seven bacterial pathogens\u00a0<\/strong><strong>with a single injection<br \/>\n<\/strong>Enrofloxacin, the active ingredient in Tenotryl\u2122 injectable solution is an efficient, broad-spectrum antibiotic that has been trusted in the U.S. swine industry for 25 years. A convenient, single-dose injection delivers swift and broad action against seven bacterial pathogens that cause swine respiratory disease (SRD), as well as colibacillosis associated with\u00a0<em>E. coli<\/em>.\n<strong>Kills key bacterial SRD pathogens and\u00a0<em>E. Coli<br \/>\n<\/em><\/strong>Tenotryl\u2122 injectable solution possesses the activity needed to kill most of the primary SRD pathogens and\u00a0<em>E. coli<\/em>. Enrofloxacin is a broad-spectrum antibiotic with low minimal inhibitory concentration (MIC) on the primary agents of SRD and colibacillosis associated with\u00a0<em>E. coli<\/em>. Its bactericidal effects are concentration or time-dependent.<sup>1<\/sup>\n<p><img loading=\"lazy\" decoding=\"async\" src=\"http:\/\/pharmgate.com\/usa\/wp-content\/uploads\/sites\/5\/2022\/07\/tenotryl-key-features.jpg\" sizes=\"auto, (max-width: 540px) 100vw, 540px\" srcset=\"https:\/\/pharmgate.com\/usa\/wp-content\/uploads\/sites\/5\/2022\/07\/tenotryl-key-features.jpg 540w, https:\/\/pharmgate.com\/usa\/wp-content\/uploads\/sites\/5\/2022\/07\/tenotryl-key-features-300x146.jpg 300w, https:\/\/pharmgate.com\/usa\/wp-content\/uploads\/sites\/5\/2022\/07\/tenotryl-key-features-260x126.jpg 260w, https:\/\/pharmgate.com\/usa\/wp-content\/uploads\/sites\/5\/2022\/07\/tenotryl-key-features-50x24.jpg 50w, https:\/\/pharmgate.com\/usa\/wp-content\/uploads\/sites\/5\/2022\/07\/tenotryl-key-features-150x73.jpg 150w\" alt=\"\" width=\"540\" height=\"262\" \/><\/p>\n<p><em>1 Gigu\u00e9re, S.; Prescot, J.F.; Dowling, P.M. 2013. Antimicrobial Therapy in Veterinary Medicine, Fifth Edition.<\/em><\/p>\n\n\t\t\t\t\t\t<h4>Label Indications and Dosage<\/h4>\n\t\t\t<div class=\"fl-builder-content fl-builder-content-6825 fl-builder-template fl-builder-module-template fl-builder-global-templates-locked\" data-post-id=\"6825\"><div class=\"fl-module fl-module-advanced-accordion fl-node-zqsht5jg387f\" data-node=\"zqsht5jg387f\">\n\t<div class=\"fl-module-content fl-node-content\">\n\t\t\r\n<div class=\"uabb-module-content uabb-adv-accordion \r\n\t\t\t\t\t\tuabb-adv-accordion-collapse\" data-enable_first=\"yes\" role=\"tablist\" >\r\n\t\t<div class=\"uabb-adv-accordion-item\"\r\n\t\t\tdata-index=\"0\">\r\n\t\t<div class=\"uabb-adv-accordion-button uabb-adv-accordion-buttonzqsht5jg387f uabb-adv-before-text\" aria-selected=\"false\" role=\"tab\" tabindex=\"0\" aria-expanded=\"true\" aria-controls=\"expandable\">\r\n\t\t\t<div class=\"uabb-adv-accordion-icon-wrap\" ><i class=\"uabb-adv-accordion-button-icon fas fa-plus\"><\/i><\/div>\t\t\t<div class=\"uabb-adv-accordion-button-label\" >Swine<\/div>\r\n\t\t\t\t\t<\/div>\r\n\t\t<div class=\"uabb-adv-accordion-content uabb-adv-accordion-contentzqsht5jg387f fl-clearfix uabb-accordion-desc uabb-text-editor\" aria-expanded=\"true\" >\r\n\t\t\t<div id=\"1513716844386-780f8db5-df08\" class=\"vc_tta-panel vc_active\" data-vc-content=\".vc_tta-panel-body\">\n<div class=\"vc_tta-panel-body\">\n<div class=\"ult_exp_section_layer ult-adjust-bottom-margin \">\n<div class=\"ult_exp_content ult_active_section\">\n<div class=\"ult_ecpsub_cont\">\n<div class=\"wpb_text_column wpb_content_element vc_custom_1659124052801\">\n<div class=\"wpb_wrapper\">\n<p><strong>Indications:<br \/>\n<\/strong>Tenotryl\u2122 (enrofloxacin) injectable solution is indicated for the treatment of swine respiratory disease (SRD) associated with\u00a0<em>Actinobacillus pleuropneumoniae, Pasteurella multocida, Haemophilus parasuis, Streptococcus suis, Bordetella bronchiseptica,\u00a0<\/em>and<em>\u00a0Mycoplasma hyopneumoniae<\/em>. It is also indicated for the control of colibacillosis in groups or pens of weaned pigs where colibacillosis associated with\u00a0<em>Escherichia coli<\/em>\u00a0has been diagnosed. To assure responsible antimicrobial drug use, enrofloxacin should only be used as a second-line drug for colibacillosis in swine following consideration of other therapeutic options.<\/p>\n<p><strong>Dosage\/Administration:<br \/>\n<\/strong><strong>(SRD Treatment):<\/strong>\u00a0Administer, by intramuscular or subcutaneous (behind the ear) injection, a single dose of 7.5 mg\/kg of body weight (3.4 mL\/100 lbs.). Administered dose volume should not exceed 5 mL per injection site.<\/p>\n<p><strong>(Colibacillosis Control):<\/strong>\u00a0Initiate administration within the first 60 days post-weaning when clinical signs are present in at least 2% of animals in the group. Administer, either by intramuscular or subcutaneous (behind the ear) injection, a single dose of 7.5 mg\/kg of body weight (3.4 mL\/100 lbs.). Administered dose volume should not exceed 5 mL per injection site.\u00a0If no improvement is noted within 48 hours, the diagnosis should be reevaluated.<br \/>\n<img loading=\"lazy\" decoding=\"async\" class=\"wp-image-6103 aligncenter\" src=\"http:\/\/pharmgate.com\/usa\/wp-content\/uploads\/sites\/5\/2022\/07\/tenotryl-table.jpg\" sizes=\"auto, (max-width: 334px) 100vw, 334px\" srcset=\"https:\/\/pharmgate.com\/usa\/wp-content\/uploads\/sites\/5\/2022\/07\/tenotryl-table.jpg 540w, https:\/\/pharmgate.com\/usa\/wp-content\/uploads\/sites\/5\/2022\/07\/tenotryl-table-239x300.jpg 239w, https:\/\/pharmgate.com\/usa\/wp-content\/uploads\/sites\/5\/2022\/07\/tenotryl-table-116x146.jpg 116w, https:\/\/pharmgate.com\/usa\/wp-content\/uploads\/sites\/5\/2022\/07\/tenotryl-table-40x50.jpg 40w, https:\/\/pharmgate.com\/usa\/wp-content\/uploads\/sites\/5\/2022\/07\/tenotryl-table-60x75.jpg 60w\" alt=\"\" width=\"334\" height=\"420\" style=\"margin-left:70px;\"\/>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<div id=\"1513264661363-6748f0e1-b32e\" class=\"vc_tta-panel vc_active\" data-vc-content=\".vc_tta-panel-body\">\n<div class=\"vc_tta-panel-heading\">\n<h4 class=\"vc_tta-panel-title vc_tta-controls-icon-position-left\"><\/h4>\n<\/div>\n<\/div>\n\t\t<\/div>\r\n\t<\/div>\r\n\t<\/div>\r\n\t<\/div>\n<\/div>\n<\/div><div class=\"uabb-js-breakpoint\" style=\"display: none;\"><\/div>\t\t\n\t\t\t\t\t\t<h4>Withdrawal Period and Safety<\/h4>\n\t\t\t<p>Animals intended for human consumption must not be slaughtered within 5 days of receiving a single-injection dose.<\/p>\n<p>The effects of enrofloxacin on swine reproductive performance, pregnancy, and lactation have not been adequately determined. The long-term effects on articular joint cartilage have not been determined in pigs above market weight.<\/p>\n\t\t\t\t\t\t<h4>Packaging<\/h4>\n\t\t\t<ul>\n<li>100 mL vials, 20 bottles\/case<\/li>\n<li>250 mL vials, 15 bottles\/case<\/li>\n<li>500 mL vials, 6 boxes\/case<\/li>\n<\/ul>\n\t\t\t\t\t\t<h4>Formulation<\/h4>\n\t\t\t<ul>\n<li>100 mg of enrofloxacin \/mL<\/li>\n<\/ul>\n\t\t\t\t\t\t<h4>FDA Status<\/h4>\n\t\t\t<p>Approved by FDA under ANADA # 200-688.<\/p>\n\t\t\t\t\t\t<h5>Swine<\/h5>\n<p><strong>Indications:<br \/><\/strong>Tenotryl\u2122 (enrofloxacin) injectable solution is indicated for the treatment of swine respiratory disease (SRD) associated with\u00a0<em>Actinobacillus pleuropneumoniae, Pasteurella multocida, Haemophilus parasuis, Streptococcus suis, Bordetella bronchiseptica,\u00a0<\/em>and<em>\u00a0Mycoplasma hyopneumoniae<\/em>. It is also indicated for the control of colibacillosis in groups or pens of weaned pigs where colibacillosis associated with\u00a0<em>Escherichia coli<\/em>\u00a0has been diagnosed. To assure responsible antimicrobial drug use, enrofloxacin should only be used as a second-line drug for colibacillosis in swine following consideration of other therapeutic options.<\/p>\n<p><strong>Dosage\/Administration:<br \/><\/strong><strong>(SRD Treatment):<\/strong>\u00a0Administer, by intramuscular or subcutaneous (behind the ear) injection, a single dose of 7.5 mg\/kg of body weight (3.4 mL\/100 lbs.). Administered dose volume should not exceed 5 mL per injection site.<\/p>\n<p><strong>(Colibacillosis Control):<\/strong>\u00a0Initiate administration within the first 60 days post-weaning when clinical signs are present in at least 2% of animals in the group. Administer, either by intramuscular or subcutaneous (behind the ear) injection, a single dose of 7.5 mg\/kg of body weight (3.4 mL\/100 lbs.). Administered dose volume should not exceed 5 mL per injection site.\u00a0If no improvement is noted within 48 hours, the diagnosis should be reevaluated.<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" src=\"http:\/\/pharmgate.com\/usa\/wp-content\/uploads\/sites\/5\/2022\/07\/tenotryl-table.jpg\" sizes=\"auto, (max-width: 334px) 100vw, 334px\" srcset=\"https:\/\/pharmgate.com\/usa\/wp-content\/uploads\/sites\/5\/2022\/07\/tenotryl-table.jpg 540w, https:\/\/pharmgate.com\/usa\/wp-content\/uploads\/sites\/5\/2022\/07\/tenotryl-table-239x300.jpg 239w, https:\/\/pharmgate.com\/usa\/wp-content\/uploads\/sites\/5\/2022\/07\/tenotryl-table-116x146.jpg 116w, https:\/\/pharmgate.com\/usa\/wp-content\/uploads\/sites\/5\/2022\/07\/tenotryl-table-40x50.jpg 40w, https:\/\/pharmgate.com\/usa\/wp-content\/uploads\/sites\/5\/2022\/07\/tenotryl-table-60x75.jpg 60w\" alt=\"\" width=\"334\" height=\"420\" \/><\/p>\n<h4>\u00a0<\/h4>\n\t\t\t\t<img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/pharmgate.com\/usa\/wp-content\/uploads\/sites\/5\/2022\/07\/tenotryl-600x600.png\" alt=\"tenotryl-600x600\" itemprop=\"image\" height=\"600\" width=\"600\" title=\"tenotryl-600x600\" onerror=\"this.style.display='none'\"  \/>\n\t\t\t\t<img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/pharmgate.com\/usa\/wp-content\/uploads\/sites\/5\/2021\/12\/Virbac-logo-125x60.png\" alt=\"Virbac-logo-125x60\" itemprop=\"image\" height=\"60\" width=\"125\" title=\"Virbac-logo-125x60\" onerror=\"this.style.display='none'\"  \/>\n\t<p>Produced by Virbac<\/p>\n\t<h4><strong><a href=\"https:\/\/vet-us.virbac.com\/home\/livestock-health\/tenotryl-enrofloxacin-injectable-solution.html\">Click to<br \/>\nlearn more<br \/>\nfrom Virbac.<\/a><\/strong><\/h4>\n\t\t\t\t<img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/pharmgate.com\/usa\/wp-content\/uploads\/sites\/5\/2017\/12\/usa-75x75.png\" alt=\"usa-75x75\" itemprop=\"image\" height=\"74\" width=\"75\" title=\"usa-75x75\" onerror=\"this.style.display='none'\"  \/>\n\t<p>Available in the USA<\/p>\n\t<em>The labeling contains complete use information, including any cautions and warnings. Always read, understand and follow the labeling and use directions.<br \/>\nSee the reverse side for use directions and additional information. \u00a9 2022 Virbac S.A. TENOTRYL is a trademark of Virbac S.A.<\/em>\n\n","protected":false},"excerpt":{"rendered":"<p>Tenotryl\u00ae (enrofloxacin) Injectable Solution Prescribing Information Product Profile Sheet Safety Data Sheet Tenotryl Info Product Description Tenotryl\u2122 (enrofloxacin) injectable solution is indicated for the treatment<\/p>\n","protected":false},"author":12,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"page-templates\/fullwidthpage.php","meta":{"_acf_changed":false,"_relevanssi_hide_post":"","_relevanssi_hide_content":"","_relevanssi_pin_for_all":"","_relevanssi_pin_keywords":"","_relevanssi_unpin_keywords":"","_relevanssi_related_keywords":"","_relevanssi_related_include_ids":"","_relevanssi_related_exclude_ids":"","_relevanssi_related_no_append":"","_relevanssi_related_not_related":"","_relevanssi_related_posts":"7542,6572,4504,221,8802,9920","_relevanssi_noindex_reason":"","footnotes":""},"country":[25],"producttype":[34],"species":[39],"class_list":["post-6094","page","type-page","status-publish","hentry","country-usa","producttype-biologics","species-swine"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v22.9 - 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