{"id":5952,"date":"2022-04-04T14:40:16","date_gmt":"2022-04-04T19:40:16","guid":{"rendered":"http:\/\/pharmgate.com\/?page_id=5952"},"modified":"2022-04-04T14:40:16","modified_gmt":"2022-04-04T19:40:16","slug":"tia","status":"publish","type":"page","link":"https:\/\/pharmgate.com\/canada\/tia\/","title":{"rendered":"Tia 12.5 Liquid Concentrate"},"content":{"rendered":"\n<h1>\n\t\tTIA<sup>\u2122<\/sup> 12.5%\n\t<\/h1>\n\t<h3>(tiamulin hydrogen fumarate)<br \/>\nLiquid Concentrate<\/h3>\n\t\t\t\t<img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/pharmgate.com\/wp-content\/uploads\/2018\/01\/Aivlosin-species-577x75.png\" alt=\"Aivlosin-species-577x75\" height=\"75\" width=\"577\" title=\"Aivlosin-species-577x75\" \/>\n\t\t\t<a href=\"\/wp-content\/uploads\/2022\/04\/VIR_TIA_Product-Info-Sheet_0002TIA-0322.pdf\" target=\"_blank\" role=\"button\" rel=\"noopener\">\n\t\t\t\t\t\tProduct Insert\n\t\t\t\t\t<\/a>\n\t\t\t<a href=\"\/wp-content\/uploads\/2022\/04\/TIA-12-5_10272021_GHS.pdf\" target=\"_blank\" role=\"button\" rel=\"noopener\">\n\t\t\t\t\t\tSafety Data Sheet\n\t\t\t\t\t<\/a>\n\t\t\t\t\t\t<h4>Product Description<\/h4>\n\t\t\t<p>TIA 12.5% (tiamulin hydrogen fumarate) liquid concentrate is used to treat swine dysentery associated with\u00a0<em>Brachyspira<\/em>\u00a0(formerly\u00a0<em>Serpulin<\/em>a or\u00a0<em>Treponema<\/em>)\u00a0<em>hyodysenteriae<\/em>\u00a0and swine pneumonia due to\u00a0<em>Actinobacillus pleuropneumoniae<\/em>, susceptible to tiamulin.<\/p>\n<ul>\n<li>Liquid concentrate for the treatment of swine dysentery associated with\u00a0<em>Brachyspira<\/em>\u00a0(formerly\u00a0<em>Serpulina<\/em>\u00a0or\u00a0<em>Treponema<\/em>)\u00a0<em>hyodysenteriae<\/em>\u00a0and swine pneumonia due to\u00a0<em>Actinobacillus pleuropneumoniae<\/em>\u00a0susceptible to tiamulin<\/li>\n<li>For use in swine drinking water<\/li>\n<li>Must be diluted before administering<\/li>\n<\/ul>\n\t\t\t\t\t\t<h4>Key Features<\/h4>\n<ul>\n<li><strong>Quick implementation:<\/strong>\u00a0Easy administration in water so you can react quickly and treat pigs as soon as a diagnosis is made.\n<ul>\n<li>It&#8217;s not necessary to wait until the next delivery of feed to get pigs started on a medicated feed additive. Nor do you have to coordinate the amount of feed to the exact number of days indicated on medicated feed additive labels.<\/li>\n<li>Pigs are likely to continue drinking water when feed intake declines as a result of illness.<sup>1<\/sup><\/li>\n<\/ul>\n<\/li>\n<li><strong>Easily mixed<\/strong>: TIA 12.5% liquid concentrate mixes easily into solution, which must be prepared fresh daily. Dosage can be adjusted to account for both the disease present and the animal weights (See Dosing Chart in the tab immediately below: Label Indications and Dosage). Do not use undiluted.<\/li>\n<li><strong>Quickly absorbed:<\/strong>\u00a0The active ingredient, tiamulin hydrogen fumarate, is readily absorbed from the gut and can be found in the blood within 30 minutes of dosing.<\/li>\n<li><strong>Works where it&#8217;s needed:<\/strong>\u00a0Achieves high tissue concentrations in the lining of the intestinal tract, lungs and tonsils.<sup>2<\/sup>\u00a0These are areas where bacteria invade and cause damage to the pig&#8217;s system.<\/li>\n<\/ul>\n<p>1 Neumann, E.J.; Ramirez, A.; Schwartz, K.J. Swine Disease Manual 5th Edition (2020) American Association of Swine Veterinarians.<\/p>\n<p>2 Walter D, Knittel J, Schwartz K, et al. Treatment and control of porcine proliferative enteropathy using different tiamulin delivery methods. J Swine Health Prod. 2001;9(3):109-115.<\/p>\n\n\t\t\t\t\t\t<h4>Label Indications and Dosage<\/h4>\n\t\t\t<div class=\"fl-builder-content fl-builder-content-6801 fl-builder-template fl-builder-module-template fl-builder-global-templates-locked\" data-post-id=\"6801\"><div class=\"fl-module fl-module-advanced-accordion fl-node-eaktl2960wsc\" data-node=\"eaktl2960wsc\">\n\t<div class=\"fl-module-content fl-node-content\">\n\t\t\r\n<div class=\"uabb-module-content uabb-adv-accordion \r\n\t\t\t\t\t\tuabb-adv-accordion-collapse\" data-enable_first=\"yes\" role=\"tablist\" >\r\n\t\t<div class=\"uabb-adv-accordion-item\"\r\n\t\t\tdata-index=\"0\">\r\n\t\t<div class=\"uabb-adv-accordion-button uabb-adv-accordion-buttoneaktl2960wsc uabb-adv-before-text\" aria-selected=\"false\" role=\"tab\" tabindex=\"0\" aria-expanded=\"true\" aria-controls=\"expandable\">\r\n\t\t\t<div class=\"uabb-adv-accordion-icon-wrap\" ><i class=\"uabb-adv-accordion-button-icon fas fa-plus\"><\/i><\/div>\t\t\t<div class=\"uabb-adv-accordion-button-label\" >Swine<\/div>\r\n\t\t\t\t\t<\/div>\r\n\t\t<div class=\"uabb-adv-accordion-content uabb-adv-accordion-contenteaktl2960wsc fl-clearfix uabb-accordion-desc uabb-text-editor\" aria-expanded=\"true\" >\r\n\t\t\t<div id=\"1513716844386-780f8db5-df08\" class=\"vc_tta-panel vc_active\" data-vc-content=\".vc_tta-panel-body\">\n<div class=\"vc_tta-panel-body\">\n<div class=\"ult_exp_section_layer ult-adjust-bottom-margin \">\n<div class=\"ult_exp_content ult_active_section\">\n<div class=\"ult_ecpsub_cont\">\n<div class=\"wpb_text_column wpb_content_element vc_custom_1651584879013\">\n<div class=\"wpb_wrapper\">\n<p><strong>Indications:<\/strong>\u00a0TIA 12.5% (tiamulin hydrogen fumarate), when administered in the drinking water for five consecutive days, is an effective antibiotic for the treatment of swine dysentery associated with\u00a0<em>Brachyspira<\/em>\u00a0(formerly\u00a0<em>Serpulina<\/em>\u00a0or\u00a0<em>Treponema<\/em>)\u00a0<em>hyodysenteriae<\/em>\u00a0susceptible to tiamulin at a dose level of 3.5 mg tiamulin hydrogen fumarate per pound of body weight daily and for treatment of swine pneumonia due to\u00a0<em>Actinobacillus pleuropneumoniae<\/em>\u00a0susceptible to tiamulin when given at 10.5 mg tiamulin hydrogen fumarate per pound of body weight daily.<\/p>\n<p>Give TIA 12.5% liquid concentrate in water to pigs for five consecutive days, with targeted dose rates based on disease to be treated and animal weight. Use as the only source of drinking water for five days. TIA 12.5% liquid concentrate is a concentrated product that must be diluted prior to administration. Prepare fresh daily. One liter of TIA 12.5% liquid concentrate will medicate 550 gallons of drinking water at 227 mg per gallon for treatment of swine dysentery or 183 gallons at 681 mg per gallon for treatment of swine pneumonia. Increase or decrease dilution rate as required to obtain proper daily drug dose (see Product Profile for dosing guide). Withdraw medicated water 3 days before slaughter after treatment at 3.5 mg per pound body weight and 7 days before slaughter after treatment at 10.5 mg per pound body weight.<\/p>\n<p><strong>Contraindications:<\/strong>\u00a0Swine being treated with TIA 12.5% (tiamulin hydrogen fumarate) should not have access to feeds containing polyether ionophores (e.g. monensin, lasalocid, narasin, salinomycin and semduramicin) as adverse reactions may occur.<\/p>\n<p><strong>Adverse Reactions:<\/strong>\u00a0Overdoses of tiamulin hydrogen fumarate have sometimes produced transitory salivation, vomiting and an apparent calming effect on the pig. If signs of toxicity occur, discontinue use of medicated water and replace with clean, fresh water. In rare cases, redness of the skin primarily over the ham and underline has been observed during medication. If these signs appear, discontinue use of this drug. Provide ample clean drinking water. Thoroughly rinse (hose down) the housing to remove urine and feces from animal contact surfaces or move the animals to clean pens. If the condition persists, consult your veterinarian.<\/p>\n<p><strong>Caution:<\/strong>\u00a0For use in drinking water of swine only - Not for use in humans.<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-full wp-image-5964\" src=\"http:\/\/pharmgate.com\/wp-content\/uploads\/2022\/04\/VIR_Tia_Chart_0222-480.png\" sizes=\"auto, (max-width: 480px) 100vw, 480px\" srcset=\"https:\/\/pharmgate.com\/wp-content\/uploads\/2022\/04\/VIR_Tia_Chart_0222-480.png 480w, https:\/\/pharmgate.com\/wp-content\/uploads\/2022\/04\/VIR_Tia_Chart_0222-480-300x239.png 300w, https:\/\/pharmgate.com\/wp-content\/uploads\/2022\/04\/VIR_Tia_Chart_0222-480-183x146.png 183w, https:\/\/pharmgate.com\/wp-content\/uploads\/2022\/04\/VIR_Tia_Chart_0222-480-50x40.png 50w, https:\/\/pharmgate.com\/wp-content\/uploads\/2022\/04\/VIR_Tia_Chart_0222-480-94x75.png 94w\" alt=\"\" width=\"480\" height=\"383\" \/><\/p>\n<p><span style=\"font-size: 10px;\">1 Prepare fresh medicated drinking water every day for the 5 day treatment period.<\/span><br \/><span style=\"font-size: 10px;\">2 Water medicated with TIA 12.5% (tiamulin hydrogen fumarate) should be the only source of drinking water during the treatment period.<\/span><br \/><span style=\"font-size: 10px;\">*3 Increase or decrease dilution rate as required to obtain proper daily drug dose.<\/span><\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<div id=\"1513264661363-6748f0e1-b32e\" class=\"vc_tta-panel\" data-vc-content=\".vc_tta-panel-body\">\n<div class=\"vc_tta-panel-heading\">\n<h4 class=\"vc_tta-panel-title vc_tta-controls-icon-position-left\">\u00a0<\/h4>\n<\/div>\n<\/div>\n\t\t<\/div>\r\n\t<\/div>\r\n\t<\/div>\r\n\t<\/div>\n<\/div>\n<\/div><div class=\"uabb-js-breakpoint\" style=\"display: none;\"><\/div>\t\t\n\t\t\t\t\t\t<h4>Withdrawal Period<\/h4>\n\t\t\t<p>Withdraw medicated water 3 days before slaughter after treatment with 3.5 mg per pound body weight and 7 days before slaughter after treatment at 10.5 mg per pound body weight.\u00a0The effects of tiamulin on swine reproductive performance, pregnancy and lactation have not been determined. Refer to the label for complete directions for use, precautions and warnings. Do not use undiluted.<\/p>\n\t\t\t\t\t\t<h4>Packaging<\/h4>\n\t\t\t<ul>\n<li>1 Liter bottles packaged 15 to a case<\/li>\n<\/ul>\n\t\t\t\t\t\t<h4>Formulation<\/h4>\n\t\t\t<ul>\n<li>12.5% (125.0 g) Tiamulin hydrogen fumarate in\u00a0 a 1 Liter bottle (33.8 fl oz; 1000 mL)<\/li>\n<\/ul>\n\t\t\t\t\t\t<h4>FDA Status<\/h4>\n\t\t\t<p>Although not a prescription product, we recommend producers work with their veterinarian to properly diagnose and treat disease.<\/p>\n<p>Restricted Drug (California): Use only as directed<\/p>\n<p>Approved by FDA under ANADA # 200-695<\/p>\n\t\t\t\t\t\t<h5>Swine<\/h5>\n<p><strong>Indications:<\/strong>\u00a0TIA 12.5% (tiamulin hydrogen fumarate), when administered in the drinking water for five consecutive days, is an effective antibiotic for the treatment of swine dysentery associated with\u00a0<em>Brachyspira<\/em>\u00a0(formerly\u00a0<em>Serpulina<\/em>\u00a0or\u00a0<em>Treponema<\/em>)\u00a0<em>hyodysenteriae<\/em>\u00a0susceptible to tiamulin at a dose level of 3.5 mg tiamulin hydrogen fumarate per pound of body weight daily and for treatment of swine pneumonia due to\u00a0<em>Actinobacillus pleuropneumoniae<\/em>\u00a0susceptible to tiamulin when given at 10.5 mg tiamulin hydrogen fumarate per pound of body weight daily.<\/p>\n<p>Give TIA 12.5% liquid concentrate in water to pigs for five consecutive days, with targeted dose rates based on disease to be treated and animal weight. Use as the only source of drinking water for five days. TIA 12.5% liquid concentrate is a concentrated product that must be diluted prior to administration. Prepare fresh daily. One liter of TIA 12.5% liquid concentrate will medicate 550 gallons of drinking water at 227 mg per gallon for treatment of swine dysentery or 183 gallons at 681 mg per gallon for treatment of swine pneumonia. Increase or decrease dilution rate as required to obtain proper daily drug dose (see Product Profile for dosing guide). Withdraw medicated water 3 days before slaughter after treatment at 3.5 mg per pound body weight and 7 days before slaughter after treatment at 10.5 mg per pound body weight.<\/p>\n<p><strong>Contraindications:<\/strong>\u00a0Swine being treated with TIA 12.5% (tiamulin hydrogen fumarate) should not have access to feeds containing polyether ionophores (e.g. monensin, lasalocid, narasin, salinomycin and semduramicin) as adverse reactions may occur.<\/p>\n<p><strong>Adverse Reactions:<\/strong>\u00a0Overdoses of tiamulin hydrogen fumarate have sometimes produced transitory salivation, vomiting and an apparent calming effect on the pig. If signs of toxicity occur, discontinue use of medicated water and replace with clean, fresh water. In rare cases, redness of the skin primarily over the ham and underline has been observed during medication. If these signs appear, discontinue use of this drug. Provide ample clean drinking water. Thoroughly rinse (hose down) the housing to remove urine and feces from animal contact surfaces or move the animals to clean pens. If the condition persists, consult your veterinarian.<\/p>\n<p><strong>Caution:<\/strong>\u00a0For use in drinking water of swine only &#8211; Not for use in humans.<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" src=\"http:\/\/pharmgate.com\/wp-content\/uploads\/2022\/04\/VIR_Tia_Chart_0222-480.png\" alt=\"\" width=\"480\" height=\"383\" \/><\/p>\n<p>1 Prepare fresh medicated drinking water every day for the 5 day treatment period.<br \/>2 Water medicated with TIA 12.5% (tiamulin hydrogen fumarate) should be the only source of drinking water during the treatment period.<br \/>*3 Increase or decrease dilution rate as required to obtain proper daily drug dose.<\/p>\n<h4>\u00a0<\/h4>\n\t\t\t\t<img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/pharmgate.com\/wp-content\/uploads\/2022\/04\/TIA-12-600x600.png\" alt=\"TIA-12-600x600\" height=\"600\" width=\"600\" title=\"TIA-12-600x600\" \/>\n\t\t\t\t<img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/pharmgate.com\/wp-content\/uploads\/2021\/12\/Virbac-logo-125x60.png\" alt=\"Virbac-logo-125x60\" height=\"60\" width=\"125\" title=\"Virbac-logo-125x60\" \/>\n\t<p>Produced by Virbac<\/p>\n\t<h4><strong><a href=\"https:\/\/vet-us.virbac.com\/tia\" target=\"_blank\" rel=\"noopener\">Click to<br \/>\nlearn more<br \/>\nfrom Virbac.<\/a><\/strong><\/h4>\n\t\t\t\t<img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/pharmgate.com\/wp-content\/uploads\/2017\/12\/usa-75x75.png\" alt=\"usa-75x75\" height=\"74\" width=\"75\" title=\"usa-75x75\" \/>\n\t<p>Available in the USA<\/p>\n\t<p><em>Consult Product Insert for use directions and additional information.<\/em><\/p>\n\n","protected":false},"excerpt":{"rendered":"<p>TIA\u2122 12.5% (tiamulin hydrogen fumarate) Liquid Concentrate Product Insert Safety Data Sheet Product Description TIA 12.5% (tiamulin hydrogen fumarate) liquid concentrate is used to treat&#8230; <\/p>\n<p><a class=\"bordered-btn read-more-link\" href=\"https:\/\/pharmgate.com\/canada\/tia\/\">Read More&#8230;<\/a><\/p>\n","protected":false},"author":12,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"page-templates\/fullwidthpage.php","meta":{"_acf_changed":false,"footnotes":""},"class_list":["post-5952","page","type-page","status-publish","hentry"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v22.9 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Tia 12.5 Liquid Concentrate - Canada<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/pharmgate.com\/canada\/tia\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Tia 12.5 Liquid Concentrate - Canada\" \/>\n<meta property=\"og:description\" content=\"TIA\u2122 12.5% (tiamulin hydrogen fumarate) Liquid Concentrate Product Insert Safety Data Sheet Product Description TIA 12.5% (tiamulin hydrogen fumarate) liquid concentrate is used to treat... 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